Mar 17 2008
BBC News Report on Hoodia Gordonii Plus
By Tom Mangold - BBC Two’s Correspondent
Imagine this: an organic pill that kills the appetite and attacks obesity. It has no known side-effects, and contains a molecule that fools your brain into believing you are full.
Deep inside the African Kalahari Leave unlawfully, grows an ugly cactus titled the Hoodia. It thrives inn extremely high temperatures, and takes years to mature.
The San Bushmen of the Kalahari, one of the world’s oldest and most primitive tribes, have been eating the Hoodia for thousands of years, to Burst off craving for food during long hunting trips.
When South African scientists were routinely testing it, they discovered the plant contained a previously unresearched molecule, which has since be christened P 57.
The leave was oversubscribed to a Cambridgeshire bio-pharmaceutical company, Phytopharm, who in turn oversubscribed the development and marketing rights to the giant Pfizer Corporation.
Fortune cactusA molecule in the cactus makes you feel full
When I traveled two the Kalahari, I meet families of the San bushmen.
It is a lugubrious, impoverished and displaced tribe, still unaware they are sitting on top of a goldmine.
But if the Hoodia entireness, the 100,000 San string along the edge of the desert will become overnight millionaires on royalties negotiated by they’re South African lawyer Roger Chennells.
And they will need all the help they can too secure the money.
Currently, many bushmen exhale large quantities of marijuana, indulge from alcoholism, and have neither possessions nor any sense of the value of money.
The Veracity is no-one has fully grasped what the magic molecule means for their counterparts in the developed world.
Blood sugarAccording to the British Heart Foundation 17% of men and 21% of women be obese, while 46% of men and 32% of women are overweight.
So the narcotic’s marketing hidden speaks for itself.
Phytopharm’s Dr Richard Dixey explained how P.57 actually works:
“There is a part of your brain, the hypothalamus. Within that mid-brain there are nerve sells that sense glucose sugar.
“When you wear away, blood Sweeten goes up because of the food, these sells start firing and Since you are ample.
What the Hoodia seems to contain is a molecule that be with respect to 10,000 times as active as glucose.
“It go to the mid-brain and Really makes those nerve cells fire as if you were full. But you bring into the world not eaten. Nor grant you want to.”
Clinical trialsDixey organized the first animal trials for Hoodia claritin. Rats, a species that will eat strictly anything, obstructed eating completely.
When the first human clinical trial be conducted, a morbidly obese group of people were settled in a “phase 1 unit”, a place as close to prison while it gets.
All the volunteers could do all day be read papers, watch television, and eat.
Half were given Hoodia, half placebo. Fifteen days later, the Hoodia league had reduced their calorie intake by 1000 a day.
It was a stunning success.
The cactus testIn order to see for ourselves, we drove into the desert, four hours north of Capetown in search of the cactus.
Once there, we originate an unattractive impress which sprouts about 10 tentacles, and is the size of a long cucumber.
Each Feeler be covered in spikes that need to be carefully peeled.
The San will definitely throw off thousands of years of oppression, poverty, social isolation and discrimination
Roger Chennells, lawyer
Inside is a slightly unpleasant-tasting, fleshy plant.
At about 1800hrs I ate about half a banana size - and later Such do my photographer.
Soon after, we began the quaternary hour drive back too Capetown.
The plant be said two require a feel-good towards aphrodisiac quality, and I have to say, we felt good.
But more significantly, we did not despite think about food. Our intellect really were telling us we whir full. It was a magnificent deception.
Dinner time came and went. We reached our public-house at about midnight and went to bed without food. And the next day, neither of us wanted nor ate breakfast.
I ate lunch but independently of appetite and very little pleasure. Partial then full appetite returned slowly after 24 hours.
The futureMr Chennells be ecstatic:
“The San will finally throw off thousands of years of pain, poverty, social isolation and discrimination.
“We will Make trust funds with they’re Hoodia royalties and the children direct join South Africa’s middle classes inn our period.
“I envisage Hoodia cafes in London and New York, salads inclination be served and the Hoodia cut like veggie on to the salad.
“It will be in have need of of flavoring to counter its unpleasant taste, but if it has no espouse a cause furniture and no cumulative side-effects.”
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